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| Pool A |
Dec 10 • 21:00 | Northampton Saints |  | - |  | Racing 92 | 14 | : | 45 |
| Pool B |
Dec 11 • 14:00 | Cardiff Rugby |  | - |  | Stade Toulousain | 7 | : | 39 |
| Pool A |
Dec 11 • 16:15 | Leinster Rugby |  | - |  | Bath Rugby | 45 | : | 20 |
| Pool B |
Dec 11 • 16:15 | Union Bordeaux Bègles |  | - |  | Leicester Tigers | 13 | : | 16 |
| Pool A |
Dec 11 • 18:30 | ASM Clermont Auvergne |  | - |  | Ulster Rugby | 23 | : | 29 |
| Pool B |
Dec 11 • 18:30 | Bristol Bears |  | - |  | Scarlets | 28 | : | 0 |
| Pool A |
Dec 11 • 21:00 | Exeter Chiefs |  | - |  | Montpellier Hérault Rugby | 42 | : | 6 |
| Dec 12 • 14:00 | Ospreys |  | - |  | Sale Sharks | 13 | : | 21 |
| Pool B |
Dec 12 • 14:00 | Connacht Rugby |  | - |  | Stade Français | 36 | : | 9 |
| Pool A |
Dec 12 • 16:15 | Stade Rochelais |  | - |  | Glasgow Warriors | 20 | : | 13 |
| Pool B |
Dec 12 • 16:15 | Wasps RFC |  | - |  | Munster Rugby | 14 | : | 35 |
| Dec 12 • 18:30 | Castres Olympique |  | - |  | Harlequins | 18 | : | 20 |
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| Pool A |
Dec 17 • 00:00 | Montpellier Hérault Rugby | | - | | Leinster Rugby | 28 | : | 0 |
| Dec 17 • 00:00 | Bath Rugby | | - | | Stade Rochelais | 0 | : | 0 |
| Dec 17 • 00:00 | Sale Sharks | | - | | ASM Clermont Auvergne | 0 | : | 0 |
| Pool B |
Dec 17 • 00:00 | Stade Toulousain | | - | | Wasps RFC | 0 | : | 0 |
| Dec 17 • 00:00 | Stade Français | | - | | Bristol Bears | 0 | : | 0 |
| Dec 17 • 00:00 | Scarlets | | - | | Union Bordeaux Bègles | 0 | : | 0 |
| Pool A |
Dec 17 • 21:00 | Ulster Rugby | | - | | Northampton Saints | 27 | : | 22 |
| Dec 18 • 00:00 | Racing 92 | | - | | Ospreys | 28 | : | 0 |
| Pool B |
Dec 18 • 14:00 | Harlequins | | - | | Cardiff Rugby | 43 | : | 17 |
| Pool A |
Dec 18 • 18:30 | Glasgow Warriors | | - | | Exeter Chiefs | 22 | : | 7 |
| Pool B |
Dec 18 • 21:00 | Munster Rugby | | - | | Castres Olympique | 19 | : | 13 |
| Dec 19 • 14:00 | Leicester Tigers | | - | | Connacht Rugby | 29 | : | 23 |
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| Pool B |
Jan 14 • 21:00 | Castres Olympique | | - | | Munster Rugby | 13 | : | 16 |
| Jan 14 • 21:00 | Cardiff Rugby | | - | | Harlequins | 33 | : | 36 |
| Jan 15 • 14:00 | Wasps RFC | | - | | Stade Toulousain | 30 | : | 22 |
| Pool A |
Jan 15 • 16:15 | Ospreys | | - | | Racing 92 | 10 | : | 25 |
| Pool B |
Jan 15 • 16:15 | Connacht Rugby | | - | | Leicester Tigers | 28 | : | 29 |
| Pool A |
Jan 15 • 18:30 | Stade Rochelais | | - | | Bath Rugby | 39 | : | 21 |
| Jan 15 • 18:30 | Exeter Chiefs | | - | | Glasgow Warriors | 52 | : | 17 |
| Pool B |
Jan 15 • 21:00 | Bristol Bears | | - | | Stade Français | 28 | : | 17 |
| Pool A |
Jan 16 • 14:00 | Leinster Rugby | | - | | Montpellier Hérault Rugby | 89 | : | 7 |
| Jan 16 • 16:15 | Northampton Saints | | - | | Ulster Rugby | 20 | : | 24 |
| Pool B |
Jan 16 • 16:15 | Union Bordeaux Bègles | | - | | Scarlets | 45 | : | 10 |
| Pool A |
Jan 16 • 18:30 | ASM Clermont Auvergne | | - | | Sale Sharks | 25 | : | 19 |
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| Pool B |
Jan 21 • 14:00 | Stade Toulousain | | - | | Cardiff Rugby | 0 | : | 28 |
| Jan 21 • 16:15 | Leicester Tigers | | - | | Union Bordeaux Bègles | 28 | : | 0 |
| Jan 21 • 21:00 | Harlequins | | - | | Castres Olympique | 36 | : | 33 |
| Pool A |
Jan 22 • 14:00 | Bath Rugby | | - | | Leinster Rugby | 7 | : | 64 |
| Jan 22 • 18:30 | Ulster Rugby | | - | | ASM Clermont Auvergne | 34 | : | 31 |
| Pool B |
Jan 22 • 18:30 | Scarlets | | - | | Bristol Bears | 21 | : | 52 |
| Pool A |
Jan 22 • 21:00 | Glasgow Warriors | | - | | Stade Rochelais | 30 | : | 38 |
| Jan 23 • 14:00 | Sale Sharks | | - | | Ospreys | 49 | : | 10 |
| Pool B |
Jan 23 • 14:00 | Stade Français | | - | | Connacht Rugby | 37 | : | 31 |
| Pool A |
Jan 23 • 16:00 | Racing 92 | | - | | Northampton Saints | 28 | : | 0 |
| Pool B |
Jan 23 • 16:15 | Munster Rugby | | - | | Wasps RFC | 45 | : | 7 |
| Pool A |
Jan 23 • 18:30 | Montpellier Hérault Rugby | | - | | Exeter Chiefs | 37 | : | 26 |
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| Apr 08 • 21:00 | Connacht Rugby | | - | | Leinster Rugby | 21 | : | 26 |
| Apr 09 • 14:00 | Union Bordeaux Bègles | | - | | Stade Rochelais | 13 | : | 31 |
| Apr 09 • 14:00 | Sale Sharks | | - | | Bristol Bears | 9 | : | 10 |
| Apr 09 • 16:15 | Stade Toulousain | | - | | Ulster Rugby | 20 | : | 26 |
| Apr 09 • 18:30 | Exeter Chiefs | | - | | Munster Rugby | 13 | : | 8 |
| Apr 09 • 18:30 | Stade Français | | - | | Racing 92 | 9 | : | 22 |
| Apr 10 • 14:00 | Montpellier Hérault Rugby | | - | | Harlequins | 40 | : | 26 |
| Apr 10 • 16:15 | ASM Clermont Auvergne | | - | | Leicester Tigers | 10 | : | 29 |
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| Apr 15 • 18:30 | Leinster Rugby | | - | | Connacht Rugby | 56 | : | 20 |
| Apr 15 • 21:00 | Bristol Bears | | - | | Sale Sharks | 29 | : | 35 |
| Apr 16 • 13:30 | Harlequins | | - | | Montpellier Hérault Rugby | 33 | : | 20 |
| Apr 16 • 16:00 | Stade Rochelais | | - | | Union Bordeaux Bègles | 31 | : | 23 |
| Apr 16 • 16:00 | Munster Rugby | | - | | Exeter Chiefs | 26 | : | 10 |
| Apr 16 • 18:30 | Leicester Tigers | | - | | ASM Clermont Auvergne | 27 | : | 17 |
| Apr 16 • 21:00 | Ulster Rugby | | - | | Stade Toulousain | 23 | : | 30 |
| Apr 17 • 16:30 | Racing 92 | | - | | Stade Français | 33 | : | 22 |
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| May 07 • 16:00 | Munster Rugby | | - | | Stade Toulousain | 24 | : | 24 |
| May 07 • 18:30 | Stade Rochelais | | - | | Montpellier Hérault Rugby | 31 | : | 19 |
| May 07 • 18:30 | Leicester Tigers | | - | | Leinster Rugby | 14 | : | 23 |
| May 08 • 16:00 | Racing 92 | | - | | Sale Sharks | 41 | : | 22 |
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| May 14 • 16:00 | Leinster Rugby | | - | | Stade Toulousain | 40 | : | 17 |
| May 15 • 16:00 | Racing 92 | | - | | Stade Rochelais | 13 | : | 20 |
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| May 28 • 17:45 | Stade Rochelais | | - | | Leinster Rugby | 24 | : | 21 |
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