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| Race | Winner | |||
| 1 |  Grand Prix of Qatar Losail International Circuit |
March 06 |  Enea Bastianini Ducati | |
| 2 |  Indonesian Grand Prix Mandalika International Street Circuit |
March 20 |  Miguel Oliveira KTM | |
| 3 |  Argentine Grand Prix Autódromo Termas de Río Hondo |
April 03 |  Aleix Espargaró Aprilia | |
| 4 |  Grand Prix of the Americas Circuit of the Americas |
April 10 | Enea Bastianini Ducati | |
| 5 | Portuguese Grand Prix Algarve International Circuit |
April 24 |  Fabio Quartararo Yamaha | |
| 6 | Spanish Grand Prix Circuito de Jerez |
May 01 | Francesco Bagnaia Ducati | |
| 7 | French Grand Prix Circuit Bugatti |
May 15 | Enea Bastianini Ducati | |
| 8 | Italian Grand Prix Mugello Circuit |
May 29 | ||
| 9 | Catalan Grand Prix Circuit de Barcelona-Catalunya |
June 05 | ||
| 10 |  German Grand Prix Sachsenring |
June 19 | ||
| 11 |  Dutch TT Circuit Assen |
June 26 | ||
| 12 |  Finnish Grand Prix Kymi Ring |
July 10 | ||
| 13 |  British Grand Prix Silverstone Circuit |
August 07 | ||
| 14 |  Austrian Grand Prix Red Bull Ring |
August 21 | ||
| 15 |  San Marino Grand Prix Misano World Circuit |
September 04 | ||
| 16 | Aragon Grand Prix MotorLand Aragón |
September 18 | ||
| 17 |  Japanese Grand Prix Twin Ring Motegi |
September 25 | ||
| 18 |  Thailand Grand Prix Buriram International Circuit |
October 02 | ||
| 19 |  Australian Grand Prix Phillip Island Grand Prix Circuit |
October 16 | ||
| 20 |  Malaysian Grand Prix Sepang International Circuit |
October 23 | ||
| 21 | Valencian Community Grand Prix Circuit Ricardo Tormo |
November 06 | ||
| Season: | ||||
