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| Nov 11 • 18:00 | CF Rusadir |  | - |  | CD Rincón | 1 | : | 2 |
| Nov 11 • 18:30 | AUGC Deportiva |  | - |  | Racing Murcia | 0 | : | 3 |
| Nov 11 • 19:00 | Real Titánico |  | - |  | CD Anaitasuna | 0 | : | 2 |
| Nov 11 • 19:00 | Racing Rioja CF |  | - |  | CD Colegios Diocesanos | 3 | : | 0 |
| Nov 11 • 19:00 | CF Montañesa |  | - |  | CD Cantolagua | 0 | : | 1 |
| Nov 11 • 19:00 | CE Cardassar |  | - |  | ADCF Épila | 0 | : | 0 |
| Nov 11 • 19:30 | UD Tomares |  | - |  | CP Chinato | 3 | : | 0 |
| Nov 11 • 20:00 | Miengo FC |  | - |  | CD Ribadumia | 0 | : | 1 |
| Nov 11 • 20:00 | Móstoles CF |  | - |  | CD Marchamalo | 0 | : | 0 |
| Nov 11 • 21:30 | UD Guía |  | - |  | CD Buñol | 0 | : | 1 |
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| Dec 15 • 18:00 | CA Pulpileño |  | - |  | CD Lugo | 1 | : | 2 |
| Dec 15 • 19:00 | CD Marchamalo | | - |  | SD Huesca | 2 | : | 3 |
| Dec 15 • 19:00 | UD Tomares | | - |  | CA Osasuna | 0 | : | 6 |
| Dec 15 • 19:00 | CD Cantolagua | | - |  | Real Valladolid | 0 | : | 5 |
| Dec 15 • 19:00 | Sestao River Club |  | - |  | CD Tenerife | 0 | : | 2 |
| Dec 15 • 19:00 | Club Portugalete |  | - |  | SD Ponferradina | 1 | : | 0 |
| Dec 15 • 20:00 | CD Ciudad de Lucena |  | - |  | Sevilla FC | 0 | : | 3 |
| Dec 15 • 20:00 | Ourense CF |  | - |  | CD Leganés | 0 | : | 1 |
| Dec 15 • 20:30 | CD Coria |  | - |  | Real Oviedo | 2 | : | 3 |
| Dec 16 • 15:15 | Coruxo FC |  | - |  | Málaga CF | 0 | : | 4 |
| Dec 16 • 15:30 | CD Lealtad |  | - |  | AD Alcorcón | 1 | : | 2 |
| Dec 16 • 16:00 | Burgos CF |  | - |  | FC Andorra | 2 | : | 0 |
| Dec 16 • 18:00 | CD Quintanar del Rey |  | - |  | Sporting de Gijon | 1 | : | 2 |
| Dec 16 • 18:00 | CE L'Hospitalet |  | - |  | UD Almeria | 1 | : | 4 |
| Dec 16 • 18:00 | San Fernando CD |  | - |  | CD Castellón | 0 | : | 2 |
| Dec 16 • 18:00 | Córdoba CF |  | - |  | Albacete Balompié | 1 | : | 0 |
| Dec 16 • 18:30 | CD Numancia |  | - |  | CF Lorca Deportiva | 4 | : | 1 |
| Dec 16 • 19:00 | Racing Murcia | | - |  | Levante UD | 0 | : | 5 |
| Dec 16 • 19:00 | CE Cardassar | | - |  | Atlético Madrid | 0 | : | 3 |
| Dec 16 • 19:00 | Terrassa FC |  | - |  | Valencia CF | 2 | : | 4 |
| Dec 16 • 19:00 | Las Rozas CF |  | - |  | CD Mirandés | 1 | : | 0 |
| Dec 16 • 19:00 | UE Llagostera |  | - |  | RCD Espanyol | 0 | : | 1 |
| Dec 16 • 19:00 | CD Ibiza Islas Pitiusas |  | - |  | CE Sabadell | 0 | : | 2 |
| Dec 16 • 19:00 | Atlético Baleares |  | - |  | CF Fuenlabrada | 0 | : | 1 |
| Dec 16 • 19:00 | SD Amorebieta |  | - |  | UD Logroñés | 1 | : | 0 |
| Dec 16 • 19:00 | Inter de Madrid |  | - |  | Linares Deportivo | 0 | : | 3 |
| Dec 16 • 19:00 | Gimnástica de Torrelavega |  | - |  | Real Zaragoza | 0 | : | 2 |
| Dec 16 • 19:30 | CD Guijuelo |  | - |  | RCD Mallorca | 0 | : | 1 |
| Dec 16 • 19:30 | Rayo Majadahonda |  | - |  | Yeclano Deportivo | 1 | : | 2 |
| Dec 16 • 20:00 | Marbella FC |  | - |  | Lleida Esportiu | 1 | : | 0 |
| Dec 16 • 20:30 | CD Calahorra |  | - |  | CF La Nucía | 0 | : | 1 |
| Dec 16 • 21:00 | CD Buñol | | - |  | Elche CF | 1 | : | 2 |
| Dec 16 • 21:00 | CD Rincón | | - |  | Deportivo Alavés | 0 | : | 2 |
| Dec 16 • 21:00 | SD Leioa |  | - |  | Villarreal CF | 0 | : | 6 |
| Dec 16 • 23:30 | CD Marino |  | - |  | UE Cornellà | 0 | : | 1 |
| Dec 17 • 17:00 | Deportivo La Coruña |  | - |  | CD El Ejido | 1 | : | 0 |
| Dec 17 • 18:00 | CDA Navalcarnero |  | - |  | CD Badajoz | 1 | : | 0 |
| Dec 17 • 19:00 | CD Anaitasuna | | - |  | Getafe CF | 1 | : | 2 |
| Dec 17 • 19:00 | CD Ribadumia | | - |  | Cádiz CF | 0 | : | 2 |
| Dec 17 • 19:00 | AD San Juan |  | - |  | Granada CF | 0 | : | 2 |
| Dec 17 • 19:00 | Gimnástica Segoviana |  | - |  | Girona FC | 0 | : | 2 |
| Dec 17 • 19:00 | CD Teruel |  | - |  | Rayo Vallecano | 2 | : | 3 |
| Dec 17 • 19:00 | UD Ibiza |  | - |  | SD Compostela | 2 | : | 1 |
| Dec 17 • 19:00 | Cultural Leonesa |  | - |  | CF Villanovense | 1 | : | 0 |
| Dec 17 • 19:00 | UD Mutilvera |  | - |  | Racing Santander | 1 | : | 0 |
| Dec 17 • 19:30 | UCAM Murcia |  | - |  | Real Betis | 0 | : | 2 |
| Dec 17 • 19:30 | SCR Peña Deportiva |  | - |  | SD Tarazona | 4 | : | 1 |
| Dec 17 • 20:00 | CD Varea |  | - |  | UD Las Palmas | 0 | : | 4 |
| Dec 17 • 20:00 | Pontevedra CF |  | - |  | FC Cartagena | 2 | : | 1 |
| Dec 17 • 20:15 | CD Alcoyano |  | - |  | CD Laredo | 4 | : | 1 |
| Dec 17 • 20:30 | Extremadura UD |  | - |  | UD Socuéllamos | 1 | : | 2 |
| Dec 17 • 21:00 | Racing Rioja CF | | - |  | SD Eibar | 0 | : | 2 |
| Dec 17 • 21:00 | UD Llanera |  | - |  | Celta de Vigo | 0 | : | 5 |
| Dec 23 • 18:30 | Haro Deportivo |  | - |  | Real Balompédica Linense | 2 | : | 1 |
| Dec 23 • 19:00 | Zamora CF |  | - |  | SD Logroñés | 2 | : | 1 |
| Dec 30 • 14:00 | UD Poblense |  | - |  | UE Olot | 1 | : | 2 |
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| Jan 05 • 17:00 | UD Ibiza | | - | | Celta de Vigo | 5 | : | 2 |
| Jan 05 • 17:00 | Córdoba CF | | - | | Getafe CF | 1 | : | 0 |
| Jan 05 • 19:00 | Zamora CF | | - | | Villarreal CF | 1 | : | 4 |
| Jan 05 • 19:00 | Linares Deportivo | | - | | Sevilla FC | 0 | : | 2 |
| Jan 05 • 21:00 | Marbella FC | | - | | Real Valladolid | 2 | : | 3 |
| Jan 05 • 21:00 | AD Alcorcón | | - | | Real Zaragoza | 2 | : | 1 |
| Jan 06 • 12:00 | Club Portugalete | | - | | Levante UD | 1 | : | 2 |
| Jan 06 • 12:00 | CF La Nucía | | - | | Elche CF | 0 | : | 1 |
| Jan 06 • 12:00 | UD Socuéllamos | | - | | CD Leganés | 0 | : | 2 |
| Jan 06 • 12:00 | CD Numancia | | - | | UD Almeria | 1 | : | 2 |
| Jan 06 • 17:00 | UD Mutilvera | | - | | Real Betis | 1 | : | 3 |
| Jan 06 • 17:00 | Cultural Leonesa | | - | | Granada CF | 1 | : | 2 |
| Jan 06 • 17:00 | Haro Deportivo | | - | | Rayo Vallecano | 1 | : | 3 |
| Jan 06 • 17:00 | CDA Navalcarnero | | - | | UD Las Palmas | 1 | : | 0 |
| Jan 06 • 18:00 | UE Cornellà | | - | | Atlético Madrid | 1 | : | 0 |
| Jan 06 • 19:00 | UE Olot | | - | | CA Osasuna | 0 | : | 3 |
| Jan 06 • 19:00 | Deportivo La Coruña | | - | | Deportivo Alavés | 0 | : | 1 |
| Jan 06 • 19:00 | Burgos CF | | - | | RCD Espanyol | 0 | : | 2 |
| Jan 06 • 20:00 | CD Castellón | | - | | CD Tenerife | 0 | : | 2 |
| Jan 06 • 21:00 | CF Fuenlabrada | | - | | RCD Mallorca | 2 | : | 2 |
| Jan 06 • 21:00 | Málaga CF | | - | | Real Oviedo | 1 | : | 0 |
| Jan 07 • 19:00 | Yeclano Deportivo | | - | | Valencia CF | 1 | : | 4 |
| Jan 07 • 19:00 | Pontevedra CF | | - | | Cádiz CF | 0 | : | 0 |
| Jan 07 • 19:00 | SCR Peña Deportiva | | - | | CE Sabadell | 0 | : | 0 |
| Jan 07 • 19:00 | Girona FC | | - | | CD Lugo | 2 | : | 1 |
| Jan 07 • 19:00 | SD Amorebieta | | - | | Sporting de Gijon | 0 | : | 1 |
| Jan 07 • 21:00 | Las Rozas CF | | - | | SD Eibar | 3 | : | 4 |
| Jan 07 • 21:00 | CD Alcoyano | | - | | SD Huesca | 2 | : | 1 |
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| Jan 16 • 12:00 | UD Almeria | | - | | Deportivo Alavés | 5 | : | 0 |
| Jan 16 • 12:00 | SCR Peña Deportiva | | - | | Real Valladolid | 1 | : | 4 |
| Jan 16 • 16:00 | Girona FC | | - | | Cádiz CF | 2 | : | 0 |
| Jan 16 • 18:00 | CF Fuenlabrada | | - | | Levante UD | 1 | : | 1 |
| Jan 16 • 20:00 | CD Leganés | | - | | Sevilla FC | 0 | : | 1 |
| Jan 16 • 22:00 | Rayo Vallecano | | - | | Elche CF | 2 | : | 0 |
| Jan 17 • 12:00 | RCD Espanyol | | - | | CA Osasuna | 0 | : | 2 |
| Jan 17 • 12:00 | Málaga CF | | - | | Granada CF | 1 | : | 2 |
| Jan 17 • 16:00 | Sporting de Gijon | | - | | Real Betis | 0 | : | 2 |
| Jan 17 • 16:00 | CDA Navalcarnero | | - | | SD Eibar | 3 | : | 1 |
| Jan 17 • 18:00 | AD Alcorcón | | - | | Valencia CF | 0 | : | 2 |
| Jan 17 • 18:00 | CD Tenerife | | - | | Villarreal CF | 0 | : | 1 |
| Jan 20 • 19:00 | Córdoba CF | | - |  | Real Sociedad | 0 | : | 2 |
| Jan 20 • 21:00 | CD Alcoyano | | - |  | Real Madrid | 2 | : | 1 |
| Jan 21 • 19:00 | UD Ibiza | | - |  | Athletic Bilbao | 1 | : | 2 |
| Jan 21 • 21:00 | UE Cornellà | | - |  | FC Barcelona | 0 | : | 2 |
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| Jan 26 • 19:00 | Real Valladolid | | - | | Levante UD | 2 | : | 4 |
| Jan 26 • 21:00 | Real Betis | | - | | Real Sociedad | 3 | : | 1 |
| Jan 26 • 21:00 | Girona FC | | - | | Villarreal CF | 0 | : | 1 |
| Jan 27 • 19:00 | Sevilla FC | | - | | Valencia CF | 3 | : | 0 |
| Jan 27 • 21:00 | UD Almeria | | - | | CA Osasuna | 0 | : | 0 |
| Jan 27 • 21:00 | Rayo Vallecano | | - | | FC Barcelona | 1 | : | 2 |
| Jan 28 • 19:00 | CDA Navalcarnero | | - | | Granada CF | 0 | : | 6 |
| Jan 28 • 21:00 | CD Alcoyano | | - | | Athletic Bilbao | 1 | : | 2 |
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| Feb 02 • 21:00 | UD Almeria | | - | | Sevilla FC | 0 | : | 1 |
| Feb 03 • 19:00 | Levante UD | | - | | Villarreal CF | 1 | : | 0 |
| Feb 03 • 21:00 | Granada CF | | - | | FC Barcelona | 3 | : | 5 |
| Feb 04 • 21:00 | Real Betis | | - | | Athletic Bilbao | 1 | : | 1 |
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| Feb 10 • 21:00 | Sevilla FC | | - | | FC Barcelona | 2 | : | 0 |
| Feb 11 • 21:00 | Athletic Bilbao | | - | | Levante UD | 1 | : | 1 |
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| Mar 03 • 21:00 | FC Barcelona | | - | | Sevilla FC | 3 | : | 0 |
| Mar 04 • 21:00 | Levante UD | | - | | Athletic Bilbao | 1 | : | 2 |
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| Apr 17 • 21:30 | FC Barcelona | | - | | Athletic Bilbao | 4 | : | 0 |
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